This is the ideal book for anyone contemplating starting a career in, or shifting their career to, studying the dynamics that drive cancer progression and its response to therapy. Topics include the theory and population genetics of cancers, genetic diversity within tumors (intra-tumor heterogeneity), understanding how mutant clones expand in tissues, the role of cancer stem cells in the dynamics of tumors, the evolution of metastasis, and how to improve cancer therapy by addressing the evolution of cancers in response to our interventions. There are also chapters on the patterns of cancer susceptibility in humans due to a mismatch between our modern environment and the environment in which our ancestors evolved, as well as a chapter on the evolution of cancer suppression mechanisms that have evolved in different species, particularly the large long-lived animals like elephants and whales that are better at suppressing cancers than humans.
This bookserves as a primer on the evolutionary and ecological theory of cancer- the framework upon which all the details of cancer may be hung. It is ideal for oncologists and cancer researchers interested in evolutionary theory, and evolutionary biologists and ecologists interested in gaining insights into cancer development and prevention.
Peter Lang AG, Internationaler Verlag der Wissenschaften
3 Mars 2011
9783035100617
How can you teach the English language to global English speakers? Can English be taught as an international language? Is it worth teaching? Isn't it more proper and profitable to learn a standard variety of English? How realistic and useful is the identification of an EIL/ELF variety? Can an EIL/ELF standard be identified? These are some of the questions the present volume has addressed with the contribution of some of the most qualified scholars in the field of English linguistics. The book is divided into four sections. The first part deals with the definition of English as an international language and English as a lingua franca. Section two takes six different teaching issues into consideration. The third section examines some learning issues and the last part of the volume debates the relationship between teacher and student in an English as a lingua franca environment.
This book offers a unique perspective on creativity in an educational environment where there is a relative dearth of literature on this subject. The authors link practice and principle to provide a practical and valuable guide for more creative language learning and teaching, using not only theoretical ideas but useful practical advice and recommendations on how better to introduce creativity into teaching and daily life. This innovative volume is sure to become a crucial reference point for teachers and practitioners of language teaching, and anyone interested in the ways in which creativity can be channelled into the teaching and learning process.
Peter Lang AG, Internationaler Verlag der Wissenschaften
12 Novembre 2012
9783035304077
While a number of published works approach the shared concerns of Ireland and Scotland, no major volume has offered a sustained and up-to-date analysis of the cultural connections between the two, despite the fact that these border crossings continue to be politically suggestive. The current collection addresses this area of comparative critical neglect, focusing on writers, from Charles Robert Maturin to Liam McIlvanney, whose work offers insights into debates about identity and politics in these two neighbour nations, too often overwhelmed by connections with their larger neighbour, England. The essays in this collection are distinct yet connected, and are designed to come together like the intricate cross-bars and precise patterning of the plaid to capture the complexity of the Celtic connections they address. They move from pre-history to postmodernism, from Gothic to Gaelic and from Macbeth to Marxism, incorporating gender and genre, and providing a detailed survey of responses to the Irish-Scottish paradigm.
While diplomacy is a well-established topic for study, global governance is a relatively new arrival to the conceptual landscape of international relations. At first glance the two exist in separate worlds. This book examines the relationship between these two concepts for the first time in a comprehensive manner.
This book develops Marcuse's critique of advanced industrial society and deploys it as a lens to critically analyze contemporary neoliberalism and its structural failures. In the chapters, Marcuse scholars explore three related topics: First, Marcuse's theory as it applies to the relationship between neoliberalism and authoritarianism, including both the historical relationship between the two and the modern re-emergence of authoritarianism and nationalism in neoliberal states today. Second, a re-examination of the relationship between neoliberal subjectivity and technological rationality that seeks to understand the stabilizing forces of neoliberal society and the way these forces register at the level of thought. Third and finally, Marcuse's conception of socialism in conversation with contemporary neoliberal rationality, and ways in which alternatives to the status quo remain possible. Together, this volume contributes to recent discussions of neoliberalism and contribute to thedevelopment of Marcuse scholarship.
This open access book shows how the #MeToo movement and revelations of sexual harassment and bullying have spurred on reform of the parliamentary workplace in four Westminster countries - Australia, Canada, New Zealand and the UK. Long-standing conventions included extreme power imbalances between parliamentarians and staff and a lack of professionalised employment practices. Codes of conduct and independent complaints bodies were resisted on grounds of parliamentary privilege: the ballot box was supposedly the best means of holding parliamentarians accountable for their conduct. The taken-for-granted status of adversarial politics and its silencing effects also rendered gendered mistreatment invisible. The authors examine the institutional backdrop and the different trajectories of reform in the four countries, with most detail on the dramatic developments in Australia after angry women marched on parliament houses in 2021. They show how the different parliaments have responded to escalating evidence of misconduct, the role of policy borrowing, and the possibilities of lasting institutional change.
